Once-Daily LYRICA CR Extended-Release Tablets 

Starting LYRICA CR

LYRICA CR for pain after shingles is available as once-daily extended-release tablets and is taken after the evening meal. It should be swallowed whole and should not be split, crushed, or chewed. Learn more about possible side effects.

LYRICA CR IS AVAILABLE IN DIFFERENT DOSAGE STRENGTHS 

Dosage strength of LYRICA CR

82.5 mg

Dosage strength of LYRICA CR

165 mg

Dosage strength of LYRICA CR

330 mg

Not actual size.

Ask your healthcare provider: Ask your healthcare provider to prescribe brand-name LYRICA and to indicate “DAW” (Dispense As Written), if appropriate, on all your LYRICA prescriptions.*

Check your pills: Some pharmacies can fill your brand-name medicine with a generic and may not be required to notify you.

  • Your pills should match one of the images pictured above
  • If your pills don’t match, speak to your pharmacist to get brand-name LYRICA
  • Ask your pharmacist to note your preference for brand-name LYRICA for future refills

*Language and requirements may vary based on your state's law.

RECOMMENDED LYRICA CR DOSING

FDA-approved
starting dose

165 mg/day

(Once a day)

FDA-approved
recommended dose range

330 mg/day

(Once a day)

660 mg/day

(Once a day)

Your LYRICA dosage may be adjusted depending on how well it works for you and how your body responds.

Start the conversation

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talk to your healthcare provider.

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IMPORTANT CONSIDERATIONS

Work with your healthcare provider to find the best dose for you

Your dose might be increased up to 660 mg/day, depending on how you respond. Your healthcare provider will adjust your dosage as needed. If you have kidney problems, your healthcare provider might prescribe a lower dose since LYRICA is mostly cleared from the body through your kidneys.

Tell your healthcare provider about all your medical conditions, including if you:

  • have or have had depression, mood problems, or suicidal thoughts or behavior
  • have breathing problems
  • have kidney problems or get kidney dialysis
  • have heart problems including heart failure
  • have a bleeding problem or a low blood platelet count
  • have abused prescription medicines, street drugs, or alcohol in the past
  • have ever had swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema)
  • plan to father a child
  • are pregnant or plan to become pregnant. It is not known if LYRICA CR will harm your unborn baby. You and your healthcare provider will have to decide if you should take LYRICA CR while you are pregnant. If you become pregnant while taking LYRICA CR, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of antiepileptic drugs, including pregabalin, the active ingredient in LYRICA CR. Information about the registry can be found at the website, www.aedpregnancyregistry.org
  • are breastfeeding or plan to breastfeed. LYRICA CR passes into your breast milk. It is not known if LYRICA CR can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take LYRICA CR. Breastfeeding is not recommended while taking LYRICA CR

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins or herbal supplements. LYRICA and other medicines may affect each other causing side effects. Especially tell your healthcare provider if you take:

  • An ACE inhibitor, used to treat many conditions, such as high blood pressure
  • Rosiglitazone, rosiglitazone and metformin, or pioglitazone for diabetes
  • Any opioid pain medicine (such as oxycodone), or medicines for anxiety (such as lorazepam) or insomnia (such as zolpidem)
  • Any medicines that make you sleepy

Possible Side Effects

The most common side effects reported with LYRICA CR include:

Dizziness

Blurry vision

Weight gain

Sleepiness

Fatigue
(tiredness)

Swelling of
hands and feet

Dry mouth

Nausea

LYRICA CR MAY CAUSE SERIOUS SIDE EFFECTS, INCLUDING:

  • Serious, even life-threatening, allergic reactions: These can be life-threatening and may include swelling of the face, mouth, lips, gums, tongue, throat or neck, trouble breathing, and rash, hives (raised bumps), or blisters. If you experience any of these symptoms, stop taking LYRICA CR and seek immediate medical attention
  • Suicidal thoughts or actions: Like other antiepileptic drugs, LYRICA CR may increase the risk of suicidal thoughts or actions in a small number of people, about 1 in 500. If you notice changes in mood, depression, or suicidal thoughts, contact your healthcare provider immediately
  • Serious breathing problems can occur when LYRICA CR is taken with other medicines that can cause severe sleepiness or decreased awareness, or when it is taken by someone who already has breathing problems. Watch for increased sleepiness or decreased breathing when starting LYRICA CR or when the dose is increased. Get help right away if breathing problems occur
  • Swelling of your hands, legs, and feet. This swelling can be a serious problem for people with heart problems
  • Dizziness and sleepiness. Do not drive a car, work with machines, or do other dangerous activities until you know how LYRICA CR affects you. Ask your healthcare provider about when it will be okay to do these activities

These are not all the possible side effects of LYRICA CR. For more information, ask your healthcare provider or pharmacist.