Fibromyalgia | Starting LYRICA® (pregabalin) CV

Starting LYRICA

For almost 20 years, LYRICA has been approved to help people manage fibromyalgia pain. Learn more about possible side effects.

LYRICA is a daily medication that is taken orally with or without food and should be taken as prescribed by your healthcare provider.

LYRICA IS AVAILABLE IN DIFFERENT DOSAGE STRENGTHS 

Dosage strength of LYRICA

25 mg

Dosage strength of LYRICA

50 mg

Dosage strength of LYRICA

75 mg

Dosage strength of LYRICA

100 mg

Dosage strength of LYRICA

150 mg

Dosage strength of LYRICA

200 mg

Dosage strength of LYRICA

225 mg

Dosage strength of LYRICA

300 mg

Not actual size.

Ask your healthcare provider: Ask your healthcare provider to prescribe brand-name LYRICA and to indicate “DAW” (Dispense As Written), if appropriate, on all your LYRICA prescriptions.*

Check your pills: Some pharmacies can fill your brand-name medicine with a generic and may not be required to notify you.

  • Your pills should match one of the images pictured above
  • If your pills don’t match, speak to your pharmacist to get brand-name LYRICA
  • Ask your pharmacist to note your preference for brand-name LYRICA for future refills

*Language and requirements may vary based on your state's law.

RECOMMENDED LYRICA DOSING

FDA-approved
starting dose

150 mg/day

(75 mg 2 times a day)

FDA-approved
recommended dose range

300 mg/day

(150 mg 2 times a day)

450 mg/day

(225 mg 2 times a day)

Your LYRICA dosage may be adjusted depending on how well it works for you and how your body responds.

Start the conversation

Get helpful tips on how to
talk to your healthcare provider about fibromyalgia pain.

Download the guide

IMPORTANT CONSIDERATIONS

Work with your healthcare provider to find the best dose for you

Your dose might be increased up to 450 mg/day, depending on how you respond. Your healthcare provider will adjust your dosage as needed. If you have kidney problems, your healthcare provider might prescribe a lower dose since LYRICA is mostly cleared from the body through your kidneys.

Tell your healthcare provider about all your medical conditions, including if you:

  • have or have had depression, mood problems, or suicidal thoughts or behavior
  • have breathing problems
  • have kidney problems or get kidney dialysis
  • have heart problems including heart failure
  • have a bleeding problem or a low blood platelet count
  • have abused prescription medicines, street drugs, or alcohol in the past
  • have ever had swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema)
  • plan to father a child
  • are pregnant or plan to become pregnant. LYRICA may harm your unborn baby. You and your healthcare provider will decide if you should take LYRICA while you are pregnant. If you become pregnant while taking LYRICA, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of antiepileptic drugs during pregnancy. Information about the registry can also be found at the website, www.aedpregnancyregistry.org
  • are breastfeeding or plan to breastfeed. LYRICA passes into your breast milk. It is not known if LYRICA can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take LYRICA. Breastfeeding is not recommended while taking LYRICA

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins or herbal supplements. LYRICA and other medicines may affect each other causing side effects. Especially tell your healthcare provider if you take:

  • An ACE inhibitor, used to treat many conditions, such as high blood pressure
  • Rosiglitazone or pioglitazone for diabetes
  • Any opioid pain medicine (such as oxycodone), or medicines for anxiety (such as lorazepam) or insomnia (such as zolpidem)
  • Any medicines that make you sleepy