WHAT IS LYRICA?
LYRICA is FDA-approved
as an add-on treatment for partial onset seizures in adults
LYRICA (pregabalin) is a prescription medicine, approved by the US Food and Drug Administration (FDA), to treat partial onset seizures in adults with epilepsy who are already taking 1 or more antiseizure drugs. There is no generic version of LYRICA.
PARTIAL ONSET SEIZURE RELIEF WITH LYRICA
HOW EFFECTIVE IS LYRICA?
In clinical studies it was shown that for some adult patients with epilepsy:
LYRICA can provide significant relief as an add-on therapy for partial onset seizures*
For some adults with epilepsy in clinical studies, LYRICA was proven as an add-on therapy to significantly reduce the frequency of partial onset seizures compared to a placebo.*
DID YOU KNOW
For some patients,
LYRICA can provide
significant relief as
an add-on therapy
for partial onset
seizures
LEARN MORE ABOUT LYRICA
HOW DOES LYRICA WORK?
LYRICA is believed to calm overactive nerves
For someone with epilepsy, calming overactive nerve cells can help control seizures, when combined with other therapies. It is unknown exactly how LYRICA works in the body. Animal studies suggest that LYRICA reduces “extra” electrical signals sent out by overactive nerves. The implication of these studies in humans is not known.
LYRICA can be taken with other medications
You most likely are taking at least one other medication to help manage your partial onset seizures. So it’s good to know that LYRICA can be taken with other medicines and has a low potential for drug interaction, but does interact with some medicines. Tell your doctor about all the medicines, vitamins, or herbal supplements you take, especially medicines that make you sleepy or any medicines mentioned below:
- Any angiotensin-converting enzyme (ACE) inhibitor, used to treat many conditions such as high blood pressure: Taking this with LYRICA may increase the chance for swelling and hives
- Avandia (rosiglitazone), Avandamet (contains rosiglitazone and metformin), or Actos (pioglitazone) used for diabetes: Taking these with LYRICA may increase the chance of weight gain or swelling of your hands or feet
- Any narcotic pain medicine (such as oxycodone), tranquilizers, or medicines for anxiety (such as lorazepam): Taking these with LYRICA may increase the chance for dizziness and sleepiness
COMMON SIDE EFFECTS
What are the common side effects of LYRICA?
Across all clinical studies, side effects were generally mild to moderate but the two most common side effects of LYRICA are dizziness and sleepiness. In these studies, dizziness occurred in 30% of LYRICA patients, compared with 8% of patients taking a placebo, and on average, lasted about 2 to 4 weeks. Sleepiness occurred in 23% of LYRICA patients, compared with 8% of patients taking a placebo and on average lasted about 4 to 8 weeks.
For some people, these went away over time. For others, these side effects lasted throughout the course of the studies.
OTHER COMMON
SIDE EFFECTS
Swelling of the hands and feet
Dry mouth
Blurred vision
Weight gain
Trouble concentrating
Feeling "high"
