ONCE-DAILY LYRICA CR EXTENDED RELEASE TABLETS
If you have diabetic nerve pain or pain after shingles, your doctor may prescribe LYRICA CR. LYRICA CR is taken just once a day after the evening meal.
LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles in adult patients. LYRICA is also indicated to treat partial-onset seizures in patients 1 month of age and older with epilepsy who take 1 or more other drugs for seizures.
How is LYRICA CR different? | ![]() | ![]() |
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How often do you take it?* | Diabetic Nerve Pain: 3 times a day Pain After Shingles: 2–3 times a day | Once a day |
Recommended starting dose (daily total) | Diabetic Nerve Pain: 150 mg/day Pain After Shingles: 150 mg/day | Diabetic Nerve Pain: 165 mg/day Pain After Shingles: 165 mg/day |
Recommended ongoing dose (daily total) | Diabetic Nerve Pain: Up to 300 mg/day† Pain After Shingles: 150-600 mg/day‡ | Diabetic Nerve Pain: 330 mg/day†† Pain After Shingles: 330-660 mg/day¶ |
If you have kidney problems or get kidney dialysis, your doctor may adjust your dosage of LYRICA or LYRICA CR.
*LYRICA/LYRICA CR is available in multiple strengths. Your doctor can adjust your dose to help you get the most from treatment.
†300 mg/day is the maximum recommended LYRICA dose for diabetic nerve pain.
††330 mg/day is the maximum recommended LYRICA CR dose for diabetic nerve pain.
‡Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg per day, and who are able to tolerate LYRICA, may be treated with up to 600 mg/day.
¶Patients who do not experience sufficient pain relief with 330 mg/day after 2 to 4 weeks of treatment and who are able to tolerate LYRICA CR may be titrated up to 660 mg/day.
Your doctor can adjust your dose to help you get the most from treatment. So it’s important to discuss your progress and any side effects you may feel with your doctor, especially in the first few weeks. Do not change your dose without talking to your doctor.
Talking to your doctor is very important if you choose to stop treatment. Do not stop taking LYRICA CR on your own. Your doctor can help you minimize potential side effects when stopping LYRICA CR.
The 2 most common side effects of LYRICA CR were dizziness and sleepiness. For some patients, these side effects went away over time. For others, these lasted throughout their treatment.
In controlled LYRICA CR trials of up to 19 weeks, 4% of patients taking LYRICA CR gained weight, compared with 2% of patients taking a placebo.
Get helpful tips on how to talk to your doctor about pain after shingles.
Eligible Patients may pay as little as $4 per Rx with the Co-Pay Savings Card.†