LYRICA and LYRICA CR are not for everyone. LYRICA and LYRICA CR may cause serious, even life-threatening, allergic reactions.
Stop taking LYRICA or LYRICA CR and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat, or neck or if you have any trouble breathing, or have a rash, hives, blisters, or skin redness.
LYRICA and LYRICA CR may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members, or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self-harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA or LYRICA CR without first talking to your doctor.
LYRICA and LYRICA CR may cause swelling of your hands, legs, and feet, which can be serious for people with heart problems. LYRICA and LYRICA CR may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA or LYRICA CR affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish or any changes in your eyesight, including blurry vision or if you have any kidney problems or get dialysis.
Some of the most common side effects of LYRICA are dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of your hands and feet, dry mouth, and feeling "high."
Some of the most common side effects of LYRICA CR are dizziness, blurry vision, weight gain, sleepiness, tiredness, swelling of hands and feet, dry mouth, and nausea.
If you have diabetes, tell your doctor about any sores or skin problems.
You may have a higher chance for swelling and hives if you are also taking angiotensin-converting enzyme (ACE) inhibitors, so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking Avandia (rosiglitazone), Avandamet (contains rosiglitazone and metformin), or Actos (pioglitazone). Do not drink alcohol while on LYRICA or LYRICA CR. You may have a higher chance for dizziness and sleepiness if you take LYRICA or LYRICA CR with alcohol, narcotic pain medicines, or medicines for anxiety.
Before you start LYRICA or LYRICA CR, tell your doctor if you are planning to father a child, if you are pregnant, or plan to become pregnant. Breastfeeding is not recommended while taking LYRICA or LYRICA CR. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA or LYRICA CR.
In studies, a specific type of blood vessel tumor was seen in mice. The meaning of these findings in humans is not known.
Do not stop taking LYRICA or LYRICA CR without talking to your doctor. If you stop suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.
LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles. LYRICA is also indicated to treat partial onset seizures in adults with epilepsy who take 1 or more drugs for seizures.
LYRICA CR is indicated to treat pain from damaged nerves (neuropathic pain) that happens with diabetes or that follows healing of shingles.
It is not known if LYRICA CR is safe and effective in children. It is not known if LYRICA CR is effective when used for the treatment of fibromyalgia or when taken with other seizure medicines for adults with partial onset seizures.
Please see full Prescribing Information and Medication Guide.