What should I tell my doctor before I start taking LYRICA?

It’s important to give your doctor your full medical history. This will make sure you have the best possible experience with LYRICA. Before taking LYRICA, tell your doctor about all your medical conditions, including if you:

  • Have or have had depression, mood problems, or suicidal thoughts or behavior
  • Have kidney problems or get kidney dialysis
  • Have heart problems, including heart failure
  • Have a bleeding problem or a low blood platelet count
  • Have abused prescription medicines, street drugs, or alcohol in the past
  • Have ever had swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema)
  • Plan to father a child
  • Are pregnant or plan to become pregnant. It is not known if LYRICA will harm your unborn baby. You and your healthcare provider will decide if you should take LYRICA while you are pregnant. If you become pregnant while taking LYRICA, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of antiepileptic drugs during pregnancy. Information about the registry can also be found at the website, http://www.aedpregnancyregistry.org/.
  • Are breastfeeding or plan to breastfeed. LYRICA passes into your breast milk. It is not known if LYRICA can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take LYRICA. Breastfeeding is not recommended while taking LYRICA.

Tell your doctor about all the medicines, vitamins, or herbal supplements you take, especially medicines that make you sleepy or any medicines mentioned below:

Any angiotensin-converting enzyme (ACE) inhibitor, used to treat many conditions such as high blood pressure: Taking this with LYRICA may increase the chance for swelling and hives.

Avandia (rosiglitazone), Avandamet (contains rosiglitazone and metformin), or Actos (pioglitazone) used for diabetes: Taking these with LYRICA may increase the chance of weight gain or swelling of your hands or feet.

Any opioids (such as oxycodone), tranquilizers, or medicines for anxiety (such as lorazepam): Taking these with LYRICA may increase the chance for dizziness and sleepiness.

Opioids (narcotic) pain medicines: Taking LYRICA in combination with these medications may reduce central nervous system activity that could lead to death.