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Question: 
Can LYRICA be taken with other medicines for partial onset seizures?
Answer: 

LYRICA has a low potential for drug interaction, but does interact with some medicines. Tell your doctor about all the medicines, vitamins, or herbal supplements you take, especially medicines that make you sleepy or any medicines mentioned below:

  • Any angiotensin-converting enzyme (ACE) inhibitor, used to treat many conditions such as high blood pressure: Taking this with LYRICA may increase the chance for swelling and hives
  • Avandia (rosiglitazone), Avandamet (contains rosiglitazone and metformin), or Actos (pioglitazone) used for diabetes: Taking these with LYRICA may increase the chance of weight gain or swelling of your hands or feet.
  • Any opioids (such as oxycodone), tranquilizers, or medicines for anxiety (such as lorazepam): Taking these with LYRICA may increase the chance for dizziness and sleepiness.
  • Opioids (narcotic) pain medicines: Taking LYRICA in combination with these medications may reduce central nervous system activity that could lead to death.
Treat: 
Partial Onset Seizures in Adults