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LYRICA and Other Medicines

Can I take LYRICA®(pregabalin) capsules CV with other medicines?

Tell your health care provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, or herbal supplements.

In studies, LYRICA was shown to have a low potential for certain types of drug interactions.

However, LYRICA and a few other drugs may affect each other, causing side effects:

  • You may have a higher chance for swelling and hives if you take angiotensin converting enzyme (ACE) inhibitors with LYRICA
  • You may have a higher chance of weight gain or swelling of your hands or feet if you take certain diabetes medicines with LYRICA
  • You may have a higher chance for dizziness and sleepiness if you take LYRICA with alcohol, narcotic pain medicines, or medicines for anxiety

Know the medicines you take. Keep a list of them with you to show your health care provider and pharmacist each time you get a new medicine. Do not start a new medicine without talking with your health care provider.

What should I tell my doctor before I start taking LYRICA?

Before taking LYRICA, tell your doctor about all your medical conditions, including if you:

  • Have or have had depression, mood problems, or suicidal thoughts or behavior
  • Have kidney problems or get kidney dialysis
  • Have heart problems, including heart failure
  • Have a bleeding problem or a low blood platelet count
  • Have abused prescription medicines, street drugs, or alcohol in the past
  • Have ever had swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema)
  • Plan to father a child
  • Are pregnant or plan to become pregnant. If you become pregnant while taking LYRICA, talk to your doctor about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of antiepileptic drugs during pregnancy
  • Are breastfeeding