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"Diabetic nerve pain felt like
my feet were on fire.”
Daniel, Produce Manager

Diabetic Nerve Pain Symptoms | LYRICA® (pregabalin) CV Safety Info

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Understanding Diabetic Nerve Pain & Symptoms

Diabetes can cause nerve damage often resulting in pain

Did you know that the pain in your feet and hands could be related to your diabetes? It starts with uncontrolled blood sugar. People with diabetes have high blood sugar levels. And over time this may cause permanent damage to the nerves. This nerve damage may cause a distinct pain called diabetic nerve pain.

Your doctor may have mentioned the term neuropathy or peripheral neuropathy. Neuropathy is nerve damage that often results in pain. Peripheral neuropathy is neuropathy that occurs in the extremities and may cause pain, such as foot pain or hand pain. The most common cause of peripheral neuropathy is diabetes.

Diabetic peripheral neuropathy is diabetes-related nerve damage most commonly felt in the feet and hands, which may or may not be painful. Some people experience this damage as pain, tingling or numbness, while others have no symptoms at all. Diabetic nerve pain from damaged nerves is a unique type of pain that is different from the pain you may experience from a headache, a sprained ankle or arthritis.

More than 29 million Americans are diagnosed with diabetes. About half of them have some form of nerve damage from the disease. Not everyone will feel this nerve damage. But about 1 in 5 people with diabetes feel shooting, burning, pins and needles pain in their feet and hands.

LYRICA is a prescription medicine taken every day to manage diabetic nerve pain. For some patients, LYRICA can provide significant relief from diabetic nerve pain, so they feel better.* LYRICA may not be appropriate for all patients with diabetic nerve pain. While there are a number of different types of neuropathies, LYRICA is only approved to treat painful diabetic peripheral neuropathy.

*Individual results may vary.

Nerve damage from diabetes can progress over time and is permanent

You may have nerve damage well before you experience its symptoms. The first time you may notice diabetic nerve pain symptoms is when the nerve damage has already progressed. While this nerve damage can cause pain, it can also result in a loss of feeling in the feet and hands. Numbness can cause cuts and foot ulcers to go unnoticed. These cuts can lead to an infection. In severe cases, an untreated infection can even result in amputation. This is why it is important to examine your feet often. You can also talk to your doctor at your next appointment and ask him or her to perform a foot exam.

Understand your symptoms

If you have diabetes and foot pain, it may be diabetic nerve pain. This pain may also be felt in the hands. And while this pain may come and go over time, it’s actually caused by permanent damage to your nerves.

In general, there are 2 types of pain: nerve pain and muscle pain. Muscle pain usually has a clear cause (injury or inflammation) and tends to go away over time. Nerve pain has many different causes. Nerve pain resulting from diabetes is the result of damaged nerves and can be long-lasting. LYRICA is a daily prescription treatment that can help relieve diabetic nerve pain.

Remember, diabetic nerve pain symptoms are a result of nerve damage caused by diabetes, and not a result of aging, weight gain, or other conditions.

Diabetic nerve pain in your feet and hands

People have many ways of describing the distinct feelings of diabetic nerve pain. Here are a few of the most common diabetic nerve pain symptoms.

  • Shooting
  • Burning
  • Pins and needles
  • Numbness
  • Electric shock-like
  • Throbbing
  • Tingling
  • Stinging
  • Stabbing
  • Radiating
  • Sensitivity to touch

For most people, this pain affects the extremities—the feet and hands.

Diabetic nerve pain can be challenging

If you experience diabetic nerve pain, you know how much it can impact you. Since it is a chronic condition, it can get worse over time. And it can be extremely frustrating.

Find out if your pain is diabetic nerve pain today

Describe your symptoms to your doctor. He or she can determine if your pain is diabetic nerve pain. Fill out our Doctor Discussion Guide. Then take your answers to your doctor.

For some patients, LYRICA can provide significant relief from diabetic nerve pain*

It’s important to keep your blood sugar under control. This may help prevent further nerve damage and loss of sensation. But you can also treat your diabetic nerve pain, a specific type of pain that requires a specific type of treatment. Make it a priority to ask your doctor about your diabetic nerve pain symptoms and available treatment options. For some patients, LYRICA can provide significant relief from diabetic nerve pain, so they feel better.*

*Individual results may vary.

On the next page, you will learn how diabetic nerve pain is diagnosed.

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LYRICA is not for everyone. LYRICA may cause serious, even life threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck or if you have any trouble breathing, or have a rash, hives or blisters.

Drugs used to treat seizures increase the risk of suicidal thoughts or behavior. LYRICA may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA without first talking to your doctor.

LYRICA may cause swelling of your hands, legs and feet, which can be serious for people with heart problems. LYRICA may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish, or any changes in your eyesight including blurry vision or if you have any kidney problems or get dialysis.

Some of the most common side effects of LYRICA are dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of your hands and feet, dry mouth, and feeling “high.” If you have diabetes, tell your doctor about any skin sores.

You may have a higher chance for swelling and hives if you are also taking angiotensin-converting enzyme (ACE) inhibitors so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking certain diabetes medicines. Do not drink alcohol while on LYRICA. You may have a higher chance for dizziness and sleepiness if you take LYRICA with alcohol, narcotic pain medicines, or medicines for anxiety.

Before you start LYRICA, tell your doctor if you are planning to father a child, or if you are pregnant, or plan to become pregnant. Breastfeeding is not recommended while taking LYRICA. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA.

In studies, a specific type of blood vessel tumor was seen in mice, but not in rats. The meaning of these findings in humans is not known.

Do not stop taking LYRICA without talking to your doctor. If you stop suddenly you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.


LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain and pain after shingles. LYRICA is also indicated to treat partial onset seizures in adults with epilepsy who take 1 or more drugs for seizures.

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